Borrelia burgdorferi antibodies in childhood scleroderma
نویسندگان
چکیده
Background and aim A possible aetiological connection between skin sclerosis and infection with Borrelia burgdorferi (Bb) has been discussed. Studies investigating the link between Bb and morphea have produced conflicting results. In several series, all patients with morphea tested have been seronegative. Other studies have found specific antibodies to Bb in between 6% and 54% of patients with morphea.
منابع مشابه
"Borrelia-associated early-onset morphea": a particular type of scleroderma in childhood and adolescence with high titer antinuclear antibodies? Results of a cohort analysis and presentation of three cases.
BACKGROUND Morphea is an inflammatory autoimmune skin sclerosis of unknown etiology. A causative role of Borrelia burgdorferi infection has been controversially discussed, but no conclusive solution has yet been achieved. OBJECTIVE Intrigued by 3 young patients with severe Borrelia-associated morphea and high-titer antinuclear antibodies, we retrospectively examined the relationship between B...
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L. Vaillant, Service de dermatologie, CHU Trousseau, F-37044 Tours Cedex (France) We read with great interest a recent article by Aberer et al. [1] published in your journal. They investigated different types of mor-phea, and 46% of their patients were sero-positive for Borrelia burgdorferi. These authors have hypothesized yet in 1985 that localized scleroderma might be a late manifestation of ...
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